Article
Functional vascular endothelial growth factor gene polymorphisms and diabetes: effect on coronary collaterals in patients with significant coronary artery disease.
Clinica chimica acta; international journal of clinical chemistry - 11 Nov 2010
Lin Tsung-Hsien, Wang Chiao-Ling, Su Ho-Ming, Hsu Po-Chao, Juo Suh-Hang Hank, Voon Wen-Chol, Shin Shyi-Jang, Lai Wen-Ter, Sheu Sheng-Hsiung
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor (VEGF) plays a pivotal role in angiogenesis. This study tested the association between functional VEGF +405 C>G (rs2010963), -2578C>A (rs699947) polymorphisms, and coronary collaterals in patients with coronary artery disease (CAD). METHOD: The collateral scoring system developed by Rentrop was used to classify 393 patients according to their collaterals as either...
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