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Article

Clinical Evolution of Epithelial–Mesenchymal Transition in Human Carcinomas

15 Nov 2019

Abstract excerpt

Abstract The significance of the phenotypic plasticity afforded by epithelial–mesenchymal transition (EMT) for cancer progression and drug resistance remains to be fully elucidated in the clinic. We evaluated epithelial–mesenchymal phenotypic characteristics across a range of tumor histologies using a validated, high-resolution digital microscopic immunofluorescence assay (IFA) that incorporates β-catenin...

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PMID: 31732654
DOI: 10.1158/0008-5472.can-18-3539

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