Article
Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype.
Breast cancer research and treatment - 1 Feb 2013
Karihtala Peeter, Auvinen Päivi, Kauppila Saila, Haapasaari Kirsi-Maria, Jukkola-Vuorinen Arja, Soini Ylermi
Abstract excerpt
In epithelial-to-mesenchymal transition (EMT) epithelial cancer cells achieve mesenchymal features, essentially helping them to metastasize. There is some evidence that EMT could be increased in triple-negative (TNBC) or basal-like breast cancers, although more precise mechanisms considering e.g. EMT-regulating transcription factors are largely unknown. We assessed immunohistochemically vimentin (separately in in...
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