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Article

The impact in older women of ovarian FMR1 genotypes and sub-genotypes on ovarian reserve.

PloS one - 1 Jan 2012

Gleicher Norbert, Weghofer Andrea, Kim Ann, Barad David H

Abstract excerpt

We recently associated ovarian FMR1genotypes and sub-genotypes with distinct ovarian aging patterns. How they impact older females is, however, unknown. We, therefore, investigated 217 consecutive first in vitro fertilization (IVF) cycles in women >40 assessing oocyte yields, stratified for better (anti-Müllerian hormone, AMH >1.05 ng/mL) or poorer (AMH ≤ 1.05 ng/mL) functional reserve (FOR)). Mean age was 42.4 ±...

Topics

Adult
Aging
Anti-Mullerian Hormone
Female
Fertilization in Vitro
Fragile X Mental Retardation Protein
Genotype
Heterozygote
Homozygote
Humans
Oocytes
Ovarian Function Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovary

Pregnancy

Source

Open in PubMed Open full text

Identifiers

PMID: 22438971
DOI: 10.1371/journal.pone.0033638
PMCID: PMC3306274

Genes

AMH
FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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