Article
Comparison of ovarian FMR1 genotypes and sub-genotypes in oocyte donors and infertile women.
Journal of assisted reproduction and genetics - 1 Jun 2012
Gleicher Norbert, Weghofer Andrea, Kim Ann, Barad David H
Abstract excerpt
PURPOSE: We recently described ovarian genotypes and sub-genotypes of the FMR1 gene with distinctly associated ovarian aging patterns, which in infertile women follow a typical X-linked distribution pattern. Whether normally fertile women, however, also demonstrate the same distribution, is unknown. METHODS: We, therefore, investigated ovarian FMR1 genotype and sub-genotype distribution in 182 oocyte donor...
Topics
- Adult
- Age Factors
- Female
- Fragile X Mental Retardation Protein
- Genotype
- Heterozygote
- Humans
- Infertility, Female
- Oocytes
- Tissue Donors
