Article
Genetic markers of ovarian follicle number and menopause in women of multiple ethnicities.
Human genetics - 1 Nov 2012
Schuh-Huerta Sonya M, Johnson Nicholas A, Rosen Mitchell P, Sternfeld Barbara, Cedars Marcelle I, Reijo Pera Renee A
Abstract excerpt
Oocyte loss has a significant impact on fertility and somatic health. Yet, we know little about factors that impact this process. We sought to identify genetic variants associated with ovarian reserve (oocyte number as measured by antral follicle count, AFC). Based on recently published genome-wide scans that identified loci associated with age of menopause, we also sought to test our hypothesis that follicle...
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