Article
Differences in ovarian aging patterns between races are associated with ovarian genotypes and sub-genotypes of the FMR1 gene.
Reproductive biology and endocrinology : RB&E - 10 Sept 2012
Gleicher Norbert, Kim Ann, Weghofer Andrea, Barad David H
Abstract excerpt
BACKGROUND: Ovarian aging patterns differ between races, and appear to affect fertility treatment outcomes. What causes these differences is, however, unknown. Variations in ovarian aging patterns have recently been associated with specific ovarian genotypes and sub-genotypes of the FMR1 gene. We, therefore, attempted to determine differences in how functional ovarian reserve (FOR) changes with advancing age...
Topics
- Adult
- Aging
- Anti-Mullerian Hormone
- Female
- Fertilization in Vitro
- Follicle Stimulating Hormone
- Fragile X Mental Retardation Protein
- Genotype
- Humans
- Infertility, Female
- Oocytes
