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Article

AMH in women with diminished ovarian reserve: potential differences by FMR1 CGG repeat level.

Journal of assisted reproduction and genetics - 1 Oct 2014

Pastore Lisa M, McMurry Timothy L, Williams Christopher D, Baker Valerie L, Young Steven L

Abstract excerpt

PURPOSE: We explored whether AMH, as a surrogate for oocyte supply, varies by FMR1 genotype in women diagnosed with diminished ovarian reserve (DOR), a subset of the Primary Ovarian Insufficiency phenotype. Research is inconsistent on the relationship between AMH and FMR1 repeat length, controlling for age. METHOD: Seventy-nine cycling women diagnosed with DOR, and without a family history of fragile X syndrome,...

Topics

Adult
Anti-Mullerian Hormone
Female
Follicle Stimulating Hormone
Fragile X Messenger Ribonucleoprotein 1
Fragile X Syndrome
Genotype
Humans
Oocytes
Ovarian Reserve
Ovary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Primary Ovarian Insufficiency

Trinucleotide Repeat Expansion

Source

Open in PubMed Open full text

Identifiers

PMID: 24938362
DOI: 10.1007/s10815-014-0276-2
PMCID: PMC4171418

Genes

AMH
FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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AMH in women with diminished ovarian reserve: potential differences by FMR1 CGG repeat level.PMID 24938362Read ↗

Diminished ovarian reserve is not observed in infertility patients with high normal CGG repeats on the fragile X mental retardation 1 (FMR1) geneSemantic proximity Read ↗

Early decline in functional ovarian reserve in young women with low (CGGn < 26) FMR1 gene alleles.Semantic proximity Read ↗

FMR1-dependent variability of ovarian aging patterns is already apparent in young oocyte donors.Semantic proximity Read ↗

Low and High-Normal FMR1 Triplet Cytosine, Guanine Guanine Repeats Affect Ovarian Reserve and Fertility in Women Who Underwent In Vitro Fertilization Treatment? Results from a Cross-Sectional Study.Semantic proximity Read ↗

Relevance of triple CGG repeats in the FMR1 gene to ovarian reserve.Semantic proximity Read ↗

Large-scale analysis of FMR1 CGG repeat length and risk of premature ovarian insufficiency in over 92 000 women.Semantic proximity Read ↗

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Intermediate CGG repeat length at the FMR1 locus is not associated with hormonal indicators of ovarian age.Semantic proximity Read ↗

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