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Article

Protein reporter bioassay systems for the phenotypic screening of candidate drugs: a mouse platform for anti-aging drug screening.

Sensors (Basel, Switzerland) - 1 Jan 2012

Chiba Takuya, Tsuchiya Tomoshi, Mori Ryoichi, Shimokawa Isao

Abstract excerpt

Recent drug discovery efforts have utilized high throughput screening (HTS) of large chemical libraries to identify compounds that modify the activity of discrete molecular targets. The molecular target approach to drug screening is widely used in the pharmaceutical and biotechnology industries, because of the amount of knowledge now available regarding protein structure that has been obtained by computer...

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PMID: 22438730
DOI: 10.3390/s120201648
PMCID: PMC3304132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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