Article
New insight into the association of apolipoprotein E genetic variants with carotid plaques and intima-media thickness.
Stroke - 1 Dec 2006
Debette Stéphanie, Lambert Jean-Charles, Gariépy Jérôme, Fievet Nathalie, Tzourio Christophe, Dartigues Jean-Françoise, Ritchie Karen, Dupuy Anne-Mary, Alpérovitch Annick, Ducimetière Pierre, Amouyel Philippe, Zureik Mahmoud
Abstract excerpt
BACKGROUND AND PURPOSE: Carotid plaques and elevated carotid artery intima-media thickness (IMT) are major predictors of vascular morbidity and mortality. Our aim was to test their association with 2 polymorphisms of the apolipoprotein E (apoE) gene, epsilon and -219G/T. METHODS: The study was performed on 5856 subjects aged > or =65 years recruited from the French population for the Three-City Study. Carotid...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.