Article
Deep annotation of mouse iso-miR and iso-moR variation.
Nucleic acids research - 1 Jul 2012
Zhou Hongjun, Arcila Mary Luz, Li Zhonghan, Lee Eun Joo, Henzler Christine, Liu Jingya, Rana Tariq M, Kosik Kenneth S
Abstract excerpt
With a dataset of more than 600 million small RNAs deeply sequenced from mouse hippocampal and staged sets of mouse cells that underwent reprogramming to induced pluripotent stem cells, we annotated the stem-loop precursors of the known miRNAs to identify isomoRs (miRNA-offset RNAs), loops, non-preferred strands, and guide strands. Products from both strands were readily detectable for most miRNAs. Changes in the...
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