Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation.

PloS one - 1 Jan 2012

Santos Daniela M, Xavier Joana M, Morgado Ana L, Solá Susana, Rodrigues Cecília M P

Abstract excerpt

Calpains are calcium regulated cysteine proteases that have been described in a wide range of cellular processes, including apoptosis, migration and cell cycle regulation. In addition, calpains have been implicated in differentiation, but their impact on neural differentiation requires further investigation. Here, we addressed the role of calpain 1 and calpain 2 in neural stem cell (NSC) self-renewal and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Calpain
Share to Dipeptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intermediate Filament Proteins

Share to Nestin

Share to Neural Stem Cells

Share to Neurogenesis

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 22432027
DOI: 10.1371/journal.pone.0033468
PMCID: PMC3303840

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation.PMID 22432027Read ↗

Neural Stem Cells (NSCs) and ProteomicsSemantic proximity Read ↗

Molecular genetic analysis of FGFR1 signalling reveals distinct roles of MAPK and PLCgamma1 activation for self-renewal of adult neural stem cells.Semantic proximity Read ↗

NPC1 Gene Deficiency Leads to Lack of Neural Stem Cell Self-Renewal and Abnormal Differentiation Through Activation of p38 Mitogen-Activated Protein Kinase SignalingSemantic proximity Read ↗

Towards an understanding of the role of Ca2+ signalling in neural stem cell activationSemantic proximity Read ↗

An Overview of Notch Signaling in Adult Tissue Renewal and MaintenanceSemantic proximity Read ↗

IL-22 Promotes Neural Stem Cell Self-Renewal in the Adult BrainSemantic proximity Read ↗

The temporal balance between self-renewal and differentiation of human neural stem cells requires the Amyloid Precursor ProteinSemantic proximity Read ↗

FIP200 is required for maintenance and differentiation of postnatal neural stem cells.Semantic proximity Read ↗

The astrocytic lineage marker calmodulin-regulated spectrin-associated protein 1 (Camsap1): phenotypic heterogeneity of newly born Camsap1-expressing cells in injured mouse brain.Semantic proximity Read ↗

Essential role of proteasomes in maintaining self-renewal in neural progenitor cells.Semantic proximity Read ↗

Characterization of a multipotent neural progenitor cell line cloned from an adult p53-/- mouse cerebellum.Semantic proximity Read ↗

Gli1 Induces G2/M Arrest and Apoptosis in Hippocampal but Not Tumor-Derived Neural Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.