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Article

FIP200 is required for maintenance and differentiation of postnatal neural stem cells.

Nature neuroscience - 1 May 2013

Wang Chenran, Liang Chun-Chi, Bian Z Christine, Zhu Yuan, Guan Jun-Lin

Abstract excerpt

Despite recent studies showing that inhibition of autophagy depletes the hematopoietic stem cell pool and increases intracellular reactive oxygen species (ROS), it remains unknown whether autophagy is essential in the maintenance of other stem cells. Moreover, it is unclear whether and how the aberrant ROS increase causes depletion of stem cells. Here we report that ablation of FIP200 (also known as Rb1cc1), a...

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Identifiers

PMID: 23542691
DOI: 10.1038/nn.3365
PMCID: PMC3637881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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