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Article

Pilot study of the association of the DDAH2 -449G polymorphism with asymmetric dimethylarginine and hemodynamic shock in pediatric sepsis.

PloS one - 1 Jan 2012

Weiss Scott L, Yu Min, Jennings Lawrence, Haymond Shannon, Zhang Gang, Wainwright Mark S

Abstract excerpt

BACKGROUND: Genetic variability in the regulation of the nitric oxide (NO) pathway may influence hemodynamic changes in pediatric sepsis. We sought to determine whether functional polymorphisms in DDAH2, which metabolizes the NO synthase inhibitor asymmetric dimethylarginine (ADMA), are associate...

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Identifiers

PMID: 22428028
DOI: 10.1371/journal.pone.0033355
PMCID: PMC3299781

Genes

DDAH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22428028-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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