Article
Neuroimmune connections in ovine pharyngeal tonsil: potential site for prion neuroinvasion.
Cell and tissue research - 1 Apr 2012
Toppets Vinciane, Piret Joelle, Kirschvink Nathalie, Lantier Frederic, Lantier Isabelle, Berthon Patricia, Daube Georges, Massart Laurent, Grobet Luc, Antoine Nadine
Abstract excerpt
Recent studies have established the involvement of nasal-associated lymphoid tissues, mainly the pharyngeal tonsil, in prion pathogenesis. However, the mechanisms of the associated neuroinvasion are still debated. To determine potential sites for prion neuroinvasion inside the ovine pharyngeal tonsil, the topography of heavy (200 kDa) and light (70 kDa) neurofilaments and of glial fibrillar acidic protein has...
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