Article
Age, scrapie status, PrP genotype and follicular dendritic cells in ovine ileal Peyer's patches.
Research in veterinary science - 1 Oct 2012
Marruchella Giuseppe, Ligios Ciriaco, Di Guardo Giovanni
Abstract excerpt
Follicular dendritic cells (FDCs) residing within ileal Peyer's patches (PPs) are of crucial relevance for sheep scrapie early pathogenesis and subsequent scrapie prion neuroinvasion. In this study, ileal PP follicles were significantly more numerous in lambs than in adult Sarda breed sheep, with significant differences being also found in lymphoid follicle area, perimeter and FDC density. Furthermore, PrPd...
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