Article
Genome-wide association study identifies a possible susceptibility locus for endometrial cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2012
Long Jirong, Zheng Wei, Xiang Yong-Bing, Lose Felicity, Thompson Deborah, Tomlinson Ian, Yu Herbert, Wentzensen Nicolas, Lambrechts Diether, Dörk Thilo, Dubrowinskaja Natalia, Goodman Marc T, Salvesen Helga B, Fasching Peter A, Scott Rodney J, Delahanty Ryan, Zheng Ying, O'Mara Tracy, Healey Catherine S, Hodgson Shirley, Risch Harvey, Yang Hannah P, Amant Frederic, Turmanov Nurzhan, Schwake Anita, Lurie Galina, Trovik Jone, Beckmann Matthias W, Ashton Katie, Ji Bu-Tian, Bao Ping-Ping, Howarth Kimberly, Lu Lingeng, Lissowska Jolanta, Coenegrachts Lieve, Kaidarova Dilyara, Dürst Matthias, Thompson Pamela J, Krakstad Camilla, Ekici Arif B, Otton Geoffrey, Shi Jiajun, Zhang Ben, Gorman Maggie, Brinton Louise, Coosemans An, Matsuno Rayna K, Halle Mari K, Hein Alexander, Proietto Anthony, Cai Hui, Lu Wei, Dunning Alison, Easton Douglas, Gao Yu-Tang, Cai Qiuyin, Spurdle Amanda B, Shu Xiao-Ou
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified more than 100 genetic loci for various cancers. However, only one is for endometrial cancer. METHODS: We conducted a three-stage GWAS including 8,492 endometrial cancer cases and 16,596 controls. After analyzing 585,963 single-nucleotide polymorphisms (SNP) in 832 cases and 2,682 controls (stage I) from the Shanghai Endometrial Cancer Genetics...
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