A Swedish genome-wide haplotype association analysis identifies novel candidate loci associated with endometrial cancer risk.

doi:10.1371/journal.pone.0316086

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A Swedish genome-wide haplotype association analysis identifies novel candidate loci associated with endometrial cancer risk.

PloS one - 1 Jan 2025

Barnekow Elin, Liu Wen, Andersson Emil, Wang Xuemin, Helgadottir Hafdis T, Thutkawkorapin Jessada, Barilla Serena, Vermani Litika, Mints Miriam, Tham Emma, Fasching Peter A, Lambrechts Diether, Amant Frédéric, Spurdle Amanda B, Hall Per, O'Mara Tracy A, Margolin Sara, Lindblom Annika

Abstract excerpt

Genome-wide association studies [GWAS] have identified a limited number of endometrial cancer risk loci by analyzing single nucleotide polymorphisms [SNPs]. We hypothesized that analyzing haplotypes rather than SNPs could provide novel and more detailed information on genetic cancer susceptibility loci. To examine the association of a SNP or haplotype with endometrial cancer risk we performed a two-stage...

Read the complete abstract on PubMed

Topics

Humans
Female
Endometrial Neoplasms
Haplotypes
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Sweden

Polymorphism, Single Nucleotide

Genetic Predisposition to Disease

Case-Control Studies

Middle Aged

Risk Factors

Genetic Loci

Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 40101186
DOI: 10.1371/journal.pone.0316086
PMCID: PMC13537468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Swedish genome-wide haplotype association analysis identifies novel candidate loci associated with endometrial cancer risk.PMID 40101186Read ↗

GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer.Semantic proximity Read ↗

Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.Semantic proximity Read ↗

Identification of nine new susceptibility loci for endometrial cancer.Semantic proximity Read ↗

A Swedish Familial Genome-Wide Haplotype Analysis Identified Five Novel Breast Cancer Susceptibility Loci on 9p24.3, 11q22.3, 15q11.2, 16q24.1 and Xq21.31.Semantic proximity Read ↗

10 Years of GWAS discovery in endometrial cancer: Aetiology, function and translation.Semantic proximity Read ↗

Five endometrial cancer risk loci identified through genome-wide association analysis.Semantic proximity Read ↗

Swedish Genome-Wide Haplotype Association Analysis Suggests Breast Cancer Loci with Varying Risk-Modifying Effects.Semantic proximity Read ↗

Genome-wide association study identifies a common variant associated with risk of endometrial cancer.Semantic proximity Read ↗

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.Semantic proximity Read ↗

Genome-Wide Association Studies of Endometrial Cancer: Latest Developments and Future DirectionsSemantic proximity Read ↗

Development and evaluation of polygenic risk scores for prediction of endometrial cancer risk in European women.Semantic proximity Read ↗

Genetic polymorphisms and endometrial cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.