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Article

Identification of an intra-molecular disulfide bond in the sodium channel β1-subunit.

Biochemical and biophysical research communications - 6 Apr 2012

Barbieri Raffaella, Baroni Debora, Moran Oscar

Abstract excerpt

The sodium channel β1 subunit is non-covalently associated with the pore-forming α-subunits, and has been proposed to act as a modulator of channel activity, regulator of channel cell surface expression and cell adhesion molecule. Its importance is evident since mutations of the β1 subunit cause neurologic and cardiovascular disorders. The first described β1 subunit mutation is the C121W, that is related to...

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PMID: 22425777
DOI: 10.1016/j.bbrc.2012.02.163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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