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Article

Functional modulation of voltage-dependent sodium channel expression by wild type and mutated C121W-β1 subunit.

Journal of bioenergetics and biomembranes - 1 Aug 2013

Baroni Debora, Barbieri Raffaella, Picco Cristiana, Moran Oscar

Abstract excerpt

Voltage dependent sodium channels are membrane proteins essential for cell excitability. They are composed by a pore-forming α-subunit, encoded in mammals by up to 9 different genes, and 4 different ancillary β-subunits. The expression pattern of the α subunit isoforms confers the distinctive functional and pharmacological properties to different excitable tissues. β subunits are important modulators of channel...

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PMID: 23584539
DOI: 10.1007/s10863-013-9510-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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