Article
Response patterns of hairy cell leukemia to B-cell mitogens and growth factors.
Blood - 15 Nov 1990
Barut B A, Cochran M K, O'Hara C, Anderson K C
Abstract excerpt
The effect of mitogens and/or recombinant B-cell growth factors (M/GFs) on the in vitro growth of hairy cells was examined. Tumor cells were isolated from the spleens of four patients with hairy cell leukemia (HCL) by Ficoll-Hypaque sedimentation and E-rosetting. Enrichment for tumor cells was confirmed with intracytoplasmic immunoglobulin (Ig) staining, tartrate resistant acid phosphatase (TRAP) staining, and...
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