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Article

Phorbol ester-induced hairy cell features on chronic lymphocytic leukemia cells in vitro.

American journal of hematology - 1 Aug 1992

al-Katib A, Wang C Y, McKenzie S, Clarkson B D, Koziner B

Abstract excerpt

Leukemic cells from eight patients with chronic lymphocytic leukemia were isolated and cultured in the continuous presence of 12-O-tetradecanoylphorbol 13-acetate (TPA) at a concentration of 1.6 x 10(-9) M for 4-10 days. Aliquots of cells were then analyzed at intervals of 24-72 hr for changes in morphology, acid phosphatase staining (AP), and expression of two hairy cell-associated surface antigens, HCL1 (CD22,...

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Identifiers

PMID: 1354412
DOI: 10.1002/ajh.2830400405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phorbol ester-induced hairy cell features on chronic lymphocytic leukemia cells in vitro.PMID 1354412Read ↗

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