Article
Flow cytometry of peripheral blood and bone marrow cells from patients with hairy cell leukemia: phenotype of hairy cells, lymphocyte subsets and detection of minimal residual disease after treatment.
Neoplasma - 1 Jan 2001
Babuŝíková O, Tomová A, Kusenda J, Gyárfás J
Abstract excerpt
By flow cytometry (FC) and an extensive panel of markers we characterized leukemia cells from the peripheral blood (PB) and bone marrow (BM) of 13 symptomatic patients with hairy cell leukemia (HCL). Hairy cells (HCs) identified in the large cell gate always expressed B-cell markers - CD19, CD20, CD22, HLA-DR, and 'HCL-restricted' markers - CD22+CD11c, CD25 and CD103. Other markers, not followed regularly, were...
Topics
- Adult
- Aged
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- Antineoplastic Agents
- B-Lymphocytes
- Blood Cells
- Bone Marrow Cells
- CD4 Antigens
- Cell Adhesion Molecules
- Cladribine
- Female
- Flow Cytometry