Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cocultivation of umbilical cord blood cells with endothelial cells leads to extensive amplification of competent CD34+CD38- cells.

Experimental hematology - 1 Jul 2000

Rosler E, Brandt J, Chute J, Hoffman R

Abstract excerpt

OBJECTIVE: In this report, methods to expand the number of human cord blood hematopoietic stem cells were explored. MATERIALS AND METHODS: CD34+ cord blood cells were expanded in the presence of various cytokine combinations in either a stroma-free cell culture system or a preformed porcine microvascular endothelial cell layer. After 7 to 21 days, stem cell number and function were monitored. In addition, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-ribosyl Cyclase
Share to ADP-ribosyl Cyclase 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antigens, CD34

Share to Endothelium

Share to Fetal Blood

Share to Granulocyte-Macrophage Colony-Stimulating Factor

Share to Organic Chemicals

Share to Stem Cell Factor

Source

Identifiers

PMID: 10907646
DOI: 10.1016/s0301-472x(00)00177-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cocultivation of umbilical cord blood cells with endothelial cells leads to extensive amplification of competent CD34+CD38- cells.PMID 10907646Read ↗

Arterial endothelium creates a permissive niche for expansion of human cord blood hematopoietic stem and progenitor cellsSemantic proximity Read ↗

Phenotypic and functional characterization of endothelial colony forming cells derived from human umbilical cord blood.Semantic proximity Read ↗

Preincubation with endothelial cell monolayers increases gene transfer efficiency into human bone marrow CD34(+)CD38(-) progenitor cells.Semantic proximity Read ↗

Co‐culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cellsSemantic proximity Read ↗

Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture systemSemantic proximity Read ↗

The potential of umbilical cord blood multipotent stem cells for nonhematopoietic tissue and cell regenerationSemantic proximity Read ↗

CD34 hybrid cells promote endothelial colony-forming cell bioactivity and therapeutic potential for ischemic diseases.Semantic proximity Read ↗

Systematic investigation of oxygen and growth factors in clinically valid ex vivo expansion of cord blood CD34(+) hematopoietic progenitor cells.Semantic proximity Read ↗

Endothelial progenitor cells—an evolving storySemantic proximity Read ↗

Rapid and efficient reprogramming of human fetal and adult blood CD34+ cells into mesenchymal stem cells with a single factorSemantic proximity Read ↗

Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity.Semantic proximity Read ↗

Purification and Long-Term Expansion of Multipotent Endothelial-Like Cells with Potential Cardiovascular RegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.