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Article

BRCA1 as a tumor suppressor linked to the regulation of epigenetic states: keeping oncomiRs under control.

Breast cancer research : BCR - 16 Mar 2012

Stefansson Olafur Andri, Esteller Manel

Abstract excerpt

BRCA1 is a tumor suppressor gene known to be implicated in the development of a subset of breast and ovarian cancers. The tumor suppressor properties of BRCA1 are generally thought to be linked to the gene's critical roles in the network of DNA damage response. In a recent report, BRCA1-mediated...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to MicroRNAs

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Share to Ovarian Neoplasms

Share to Promoter Regions, Genetic

Source

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Identifiers

PMID: 22423979
DOI: 10.1186/bcr3119
PMCID: PMC3446364

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22423979-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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