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Integrative Genomic Analysis and Functional Studies Reveal GP5, GRN, MPO and MCAM as Causal Protein Biomarkers for Platelet Traits

2019-11-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Mean platelet volume (MPV) and platelet count (PLT) are platelet measures that have been linked to cardiovascular disease (CVD) and mortality risk. Identifying protein biomarkers for these measures may yield insights into CVD mechanisms. <h4>Objective</h4> We aimed to identify causal protein biomarkers for MPV and PLT among 71 CVD-related plasma proteins measured in Framingh...

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Literature Corpus work
9d49d0c9-6c76-5105-904c-7045ee93d4dc
DOI
10.1101/854216
Open publication

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Integrative Genomic Analysis and Functional Studies Reveal GP5, GRN, MPO and MCAM as Causal Protein Biomarkers for Platelet TraitsDOI 10.1101/854216
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