Sequence variants in three loci influence monocyte counts and erythrocyte volume.

doi:10.1016/j.ajhg.2009.10.005

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Article

Sequence variants in three loci influence monocyte counts and erythrocyte volume.

American journal of human genetics - 1 Nov 2009

Ferreira Manuel A R, Hottenga Jouke-Jan, Warrington Nicole M, Medland Sarah E, Willemsen Gonneke, Lawrence Robert W, Gordon Scott, de Geus Eco J C, Henders Anjali K, Smit Johannes H, Campbell Megan J, Wallace Leanne, Evans David M, Wright Margaret J, Nyholt Dale R, James Alan L, Beilby John P, Penninx Brenda W, Palmer Lyle J, Frazer Ian H, Montgomery Grant W, Martin Nicholas G, Boomsma Dorret I

Abstract excerpt

Blood cells participate in vital physiological processes, and their numbers are tightly regulated so that homeostasis is maintained. Disruption of key regulatory mechanisms underlies many blood-related Mendelian diseases but also contributes to more common disorders, including atherosclerosis. We searched for quantitative trait loci (QTL) for hematology traits through a whole-genome association study, because...

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PMID: 19853236
DOI: 10.1016/j.ajhg.2009.10.005
PMCID: PMC2775836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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