Article
Unusual high dose of tacrolimus in liver transplant patient, a case report.
International journal of clinical pharmacy - 1 Apr 2012
Provenzani Alessio, Notarbartolo Monica, Labbozzetta Manuela, Poma Paola, D'Antoni Adele, Polidori Piera, Vizzini Giovanni, D'Alessandro Natale
Abstract excerpt
CASE: We describe the case of a liver transplant patient who had great difficulty in reaching the desired trough blood levels despite the use of high dose tacrolimus. The patient was homozygous for the CYP3A5*3 allele. However, the respective donor carried the wild-type CYP3A5*1/*1 genotype. Rega...
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