Impact of the Reelin signaling cascade (ligands-receptors-adaptor complex) on cognition in schizophrenia.

doi:10.1002/ajmg.b.32042

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Article

Impact of the Reelin signaling cascade (ligands-receptors-adaptor complex) on cognition in schizophrenia.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2012

Verbrugghe Phebe, Bouwer Sonja, Wiltshire Steven, Carter Kim, Chandler David, Cooper Matthew, Morar Bharti, Razif Muhammad F M, Henders Anjali, Badcock Johanna C, Dragovic Milan, Carr Vaughan, Almeida Osvaldo P, Flicker Leon, Montgomery Grant, Jablensky Assen, Kalaydjieva Luba

Abstract excerpt

Our previous neurocognitive studies of schizophrenia outlined two clusters of affected subjects--cognitively spared (CS) and cognitive deficit (CD), the latter's characteristics pointing to developmental origins and impaired synaptic plasticity. Here we investigate the contribution of polymorphisms in major regulators of these processes to susceptibility to schizophrenia and to CD in patients. We examine...

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Identifiers

PMID: 22419519
DOI: 10.1002/ajmg.b.32042

Genes

APOE
DAB1
VLDLR
RELN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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