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Article

Translating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies.

British journal of pharmacology - 1 Oct 2017

O'Tuathaigh Colm M P, Moran Paula M, Zhen Xuechu C, Waddington John L

Abstract excerpt

The presence and severity of cognitive symptoms, including working memory, executive dysfunction and attentional impairment, contributes materially to functional impairment in schizophrenia. Cognitive symptoms have proved to be resistant to both first- and second-generation antipsychotic drugs. Efforts to develop a consensus set of cognitive domains that are both disrupted in schizophrenia and are amenable to...

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Identifiers

PMID: 28667666
DOI: 10.1111/bph.13938
PMCID: PMC5595756

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