Article
A new assay for CCR5del32 mutation: genotyping through the number of fragments amplified.
Journal of biomedical nanotechnology - 1 Dec 2011
Wang Qinglin, Xiao Li, Zhang Jia, He Nongyue, Lu Xueguan, Li Ping, Li Kai
Abstract excerpt
CCR5 is a coreceptor for the entry of HIV into CD4+ cells and some of its natural mutants possess potential protection against HIV-1 infection. Individuals with the CCR5-delta32 genotype have a lower possibility of being infected with HIV and take longer to progress to AIDS if infected. The present study demonstrated a new primer extension assay for genetic analysis of the CCR5del32 mutation: each genotype is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
