Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility.

doi:10.1016/j.schres.2012.10.008

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Article

Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility.

Schizophrenia research - 1 Dec 2012

Li Ming, Wang Yi, Zheng Xue-bin, Ikeda Masashi, Iwata Nakao, Luo Xiong-jian, Chong Siow-Ann, Lee Jimmy, Rietschel Marcella, Zhang Fengyu, Müller-Myhsok Bertram, Cichon Sven, Weinberger Daniel R, Mattheisen Manuel, Schulze Thomas G, Martin Nicholas G, Mitchell Philip B, Schofield Peter R, Liu Jian-jun, Su Bing

Abstract excerpt

Recent genome-wide association studies have reported a set of schizophrenia susceptibility genes, but many of them await further replications in additional samples. Here we analyzed 5 genome-wide supported variants in a Han Chinese sample, and the variant rs2312147 at VRK2 showed significant association, which was confirmed in the meta-analysis combining multiple Asian and European samples (P=3.17×10(-4),...

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Identifiers

PMID: 23102693
DOI: 10.1016/j.schres.2012.10.008

Genes

VRK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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