Article
Comparison of the convergent receptor utilization of a retargeted feline leukemia virus envelope with a naturally-occurring porcine endogenous retrovirus A.
Virology - 5 Jun 2012
Mazari Peter M, Argaw Takele, Valdivieso Leonardo, Zhang Xia, Marcucci Katherine T, Salomon Daniel R, Wilson Carolyn A, Roth Monica J
Abstract excerpt
In vitro screening of randomized FeLV Envelope libraries identified the CP isolate, which enters cells through HuPAR-1, one of two human receptors utilized by porcine endogenous retrovirus-A (PERV-A), a distantly related gammaretrovirus. The CP and PERV-A Envs however, share little amino acid homology. Their receptor utilization was examined to define the common receptor usage of these disparate viral Envs. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
