Article
Envelope determinants for dual-receptor specificity in feline leukemia virus subgroup A and T variants.
Journal of virology - 1 Feb 2006
Cheng Heather H, Anderson Maria M, Hankenson F Claire, Johnston Lily, Kotwaliwale Chitra V, Overbaugh Julie
Abstract excerpt
Gammaretroviruses, including the subgroups A, B, and C of feline leukemia virus (FeLV), use a multiple-membrane-spanning transport protein as a receptor. In some cases, such as FeLV-T, a nonclassical receptor that includes both a transport protein (Pit1) and a soluble cofactor (FeLIX) is required for entry. To define which regions confer specificity to classical versus nonclassical receptor pathways, we...
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