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Article

Whole exome sequencing (WES) on formalin-fixed, paraffin-embedded (FFPE) tumor tissue in gastrointestinal stromal tumors (GIST).

BMC genomics - 3 Nov 2015

Astolfi Annalisa, Urbini Milena, Indio Valentina, Nannini Margherita, Genovese Chiara Giusy, Santini Donatella, Saponara Maristella, Mandrioli Anna, Ercolani Giorgio, Brandi Giovanni, Biasco Guido, Pantaleo Maria A

Abstract excerpt

BACKGROUND: Next generation sequencing (NGS) technology has been rapidly introduced into basic and translational research in oncology, but the reduced availability of fresh frozen (FF) tumor tissues and the poor quality of DNA extracted from formalin-fixed, paraffin-embedded (FFPE) has significantly impaired this process in the field of solid tumors. To evaluate if data generated from FFPE material can be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26531060
DOI: 10.1186/s12864-015-1982-6
PMCID: PMC4630927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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