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Article

Sustained viral load reduction in treatment-naive HCV genotype 1 infected patients after therapeutic peptide vaccination.

Vaccine - 19 Apr 2012

Klade Christoph S, Schuller Elisabeth, Boehm Thomas, von Gabain Alexander, Manns Michael P

Abstract excerpt

BACKGROUND: Novel antivirals augment treatment efficacy in chronic HCV infection, to overcome limitations on safety profile alternative approaches are warranted. The effect of a therapeutic peptide vaccine on HCV viral load was investigated in treatment-naïve genotype 1 HCV patients. METHODS: Fifty patients received 8 intradermal IC41 vaccinations biweekly with topical application of the TLR7 agonist imiquimod...

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Source

Identifiers

PMID: 22401867
DOI: 10.1016/j.vaccine.2012.02.070

Genes

TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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