Article
Common variants in SOCS7 gene predict obesity, disturbances in lipid metabolism and insulin resistance.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 May 2013
Tellechea M L, Steinhardt A Penas, Rodriguez G, Taverna M J, Poskus E, Frechtel G
Abstract excerpt
BACKGROUND AND AIMS: Specific Suppressor of Cytokine Signaling (SOCS) members, such as SOCS7, may play a role in the development of insulin resistance (IR) owing to their ability to inhibit insulin signaling pathways. The objective was to explore the association between common variants and related haplotypes in SOCS7 gene and metabolic traits related to obesity, lipid metabolism and IR. METHODS AND RESULTS: 780...
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