Germline Polymorphisms of the VEGF Pathway Predict Recurrence in Nonadvanced Differentiated Thyroid Cancer.

doi:10.1210/jc.2016-2555

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Article

Germline Polymorphisms of the VEGF Pathway Predict Recurrence in Nonadvanced Differentiated Thyroid Cancer.

The Journal of clinical endocrinology and metabolism - 1 Feb 2017

Marotta Vincenzo, Sciammarella Concetta, Capasso Mario, Testori Alessandro, Pivonello Claudia, Chiofalo Maria Grazia, Gambardella Claudio, Grasso Marica, Antonino Antonio, Annunziata Annamaria, Macchia Paolo Emidio, Pivonello Rosario, Santini Luigi, Botti Gerardo, Losito Simona, Pezzullo Luciano, Colao Annamaria, Faggiano Antongiulio

Abstract excerpt

Context: Tumor angiogenesis is determined by host genetic background rather than environment. Germline single nucleotide polymorphisms (SNPs) of the vascular endothelial growth factor (VEGF) pathway have demonstrated prognostic value in different tumors. Objectives: Our main objective was to test the prognostic value of germline SNPs of the VEGF pathway in nonadvanced differentiated thyroid cancer (DTC)....

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PMID: 27849428
DOI: 10.1210/jc.2016-2555

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