Article
Prognostic value of the KRAS G12V mutation in 841 surgically resected Caucasian lung adenocarcinoma cases.
British journal of cancer - 20 Oct 2015
Renaud Stéphane, Falcoz Pierre-Emmanuel, Schaëffer Mickaël, Guenot Dominique, Romain Benoit, Olland Anne, Reeb Jérémie, Santelmo Nicola, Chenard Marie-Pierre, Legrain Michèle, Voegeli Anne-Claire, Beau-Faller Michèle, Massard Gilbert
Abstract excerpt
BACKGROUND: Identifying patients who will experience lung cancer recurrence after surgery remains a challenge. We aimed to evaluate whether mutant forms of epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene homolog (KRAS) (mEGFR and mKRAS) are useful biomarkers in resected non-small cell lung cancer (NSCLC). METHODS: We retrospectively reviewed data from 841 patients who underwent...
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