[Application of multifactor dimensionality reduction on the interactions between gene-gene, gene-environment and the risk sporadic colorectal cancer in Chinese population].

Abstract excerpt

OBJECTIVE: To identify the association between risk of sporadic colorectal cancer and the common single nucleotide polymorphisms (SNPs) in DNA repairs genes, gene to gene interactions among them and their gene to environment interactions with common environmental factors. METHODS: In this population-based case-control study, 206 primary colorectal cancer cases and 845 cancer-free healthy controls were enrolled....

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