Article
The different function of single phosphorylation sites of Drosophila melanogaster lamin Dm and lamin C.
PloS one - 1 Jan 2012
Zaremba-Czogalla Magdalena, Piekarowicz Katarzyna, Wachowicz Katarzyna, Kozioł Katarzyna, Dubińska-Magiera Magda, Rzepecki Ryszard
Abstract excerpt
Lamins' functions are regulated by phosphorylation at specific sites but our understanding of the role of such modifications is practically limited to the function of cdc 2 (cdk1) kinase sites in depolymerization of the nuclear lamina during mitosis. In our study we used Drosophila lamin Dm (B-type) to examine the function of particular phosphorylation sites using pseudophosphorylated mutants mimicking single...
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