Article
p34cdc2 acts as a lamin kinase in fission yeast.
The Journal of cell biology - 1 Mar 1991
Enoch T, Peter M, Nurse P, Nigg E A
Abstract excerpt
The nuclear lamina is an intermediate filament network that underlies the nuclear membrane in higher eukaryotic cells. During mitosis in higher eukaryotes, nuclear lamins are phosphorylated by a mitosis-specific kinase and this induces disassembly of the lamina structure. Recently, p34cdc2 protein kinase purified from starfish has been shown to induce phosphorylation of lamin proteins and disassembly of the...
Topics
- Animals
- CDC2 Protein Kinase
- Chickens
- Fluorescent Antibody Technique
- Gene Expression
- Lamin Type B
- Lamins
- Mitosis
- Mutation
- Nuclear Proteins
- Phosphorylation
- Precipitin Tests