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Article

Astrocyte-Specific Expression Patterns Associated with the PDGF-Induced Glioma Microenvironment

29 Feb 2012

Abstract excerpt

BACKGROUND: The tumor microenvironment contains normal, non-neoplastic cells that may contribute to tumor growth and maintenance. Within PDGF-driven murine gliomas, tumor-associated astrocytes (TAAs) are a large component of the tumor microenvironment. The function of non-neoplastic astrocytes in the glioma microenvironment has not been fully elucidated; moreover, the differences between these astrocytes and...

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PMID: 22393407
DOI: 10.1371/journal.pone.0032453

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