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Article

Identification of a poor-prognosis BRAF-mutant-like population of patients with colon cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Apr 2012

Popovici Vlad, Budinska Eva, Tejpar Sabine, Weinrich Scott, Estrella Heather, Hodgson Graeme, Van Cutsem Eric, Xie Tao, Bosman Fred T, Roth Arnaud D, Delorenzi Mauro

Abstract excerpt

PURPOSE: Our purpose was development and assessment of a BRAF-mutant gene expression signature for colon cancer (CC) and the study of its prognostic implications. MATERIALS AND METHODS: A set of 668 stage II and III CC samples from the PETACC-3 (Pan-European Trails in Alimentary Tract Cancers) cl...

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Source

Identifiers

PMID: 22393095
DOI: 10.1200/JCO.2011.39.5814

Genes

BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22393095-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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