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Article

[Extramedullary onset of mixed phenotype acute leukemia with MLL gene rearrangement].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Mar 2013

Kawashima Ichiro, Shobu Yuki, Yamamoto Takeo, Hamanaka Satoshi, Nozaki Yumi, Nakajima Kei, Mitsumori Toru, Kirito Keita

Abstract excerpt

Rearrangements of the mixed lineage leukemia MLL gene at chromosome 11q23 are common chromosomal abnormalities in human leukemia. MLL fused with numerous partner genes causes different leukemia phenotypes that depend on the function of partner genes. MLLT3-MLL is generated by translocation t(9;11), which primarily induces acute myeloid leukemia in humans, whereas MLLT3-MLL induces ALL or biphenotypic leukemia in...

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Share to MPO gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Myeloid-Lymphoid Leukemia Protein

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Share to Transcription Factors

Share to Translocation, Genetic

Source

Identifiers

PMID: 23676645

Genes

MLLT3
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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