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Article

JunB contributes to Id2 repression and the epithelial–mesenchymal transition in response to transforming growth factor–β

5 Mar 2012

Abstract excerpt

The process of epithelial-mesenchymal transition (EMT) in response to transforming growth factor-β (TGF-β) contributes to tissue fibrosis, wound healing, and cancer via a mechanism that is not fully understood. This study identifies a critical role of JunB in the EMT and profibrotic responses to TGF-β. Depletion of JunB by small interfering ribonucleic acid abrogates TGF-β-induced disruption of cell-cell...

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PMID: 22391036
DOI: 10.1083/jcb.201109045

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JunB contributes to Id2 repression and the epithelial–mesenchymal transition in response to transforming growth factor–βPMID 22391036Read ↗

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