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Article

Association of SLC11A1 (NRAMP1) polymorphisms with pulmonary Mycobacterium avium complex infection.

Human immunology - 1 May 2012

Sapkota Bishwa Raj, Hijikata Minako, Matsushita Ikumi, Tanaka Goh, Ieki Ryuji, Kobayashi Nobuyuki, Toyota Emiko, Nagai Hideaki, Kurashima Atsuyuki, Tokunaga Katsushi, Keicho Naoto

Abstract excerpt

Although genetic variants in SLC11A1 (NRAMP1) have been associated with mycobacterial diseases, these findings have not been extensively validated in pulmonary Mycobacterium avium complex (MAC) infection. This study investigated the genomic structure of SLC11A1 and its association with MAC infection. Nineteen polymorphic loci were genotyped in European descendents and the Japanese population. Linkage...

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PMID: 22387151
DOI: 10.1016/j.humimm.2012.02.008

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