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Article

Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure.

PloS one - 1 Jan 2012

Mwai Leah, Diriye Abdi, Masseno Victor, Muriithi Steven, Feltwell Theresa, Musyoki Jennifer, Lemieux Jacob, Feller Avi, Mair Gunnar R, Marsh Kevin, Newbold Chris, Nzila Alexis, Carret Céline K

Abstract excerpt

The combination therapy of the Artemisinin-derivative Artemether (ART) with Lumefantrine (LM) (Coartem®) is an important malaria treatment regimen in many endemic countries. Resistance to Artemisinin has already been reported, and it is feared that LM resistance (LMR) could also evolve quickly. T...

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PMID: 22384044
DOI: 10.1371/journal.pone.0031623
PMCID: PMC3288012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22384044-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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