Article
Potential association of DDR1 genetic variant with FEV1 decline by aspirin provocation in asthmatics.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Apr 2012
Kim Jason Yongha, Kim Jeong-Hyun, Park Byung-Lae, Pasaje Charisse Flerida A, Bae Joon Seol, Uh Soo-Taek, Kim Yong-Hoon, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Choi Byoung Whui, Park Jong Sook, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: The discoidin domain receptor tyrosine kinase 1 (DDR1) is positioned within the major histocompatibility complex (MHC) region which plays an important role in the immune system. In addition, DDR1 has been elucidated to be downregulated during the epithelial-mesenchymal transition of bronchial epithelium. OBJECTIVE: To investigate the potential genetic associations between DDR1 and aspirin-exacerbated...
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