Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

α-Melanocyte-Stimulating Hormone Counteracts the Suppressive Effect of UVB on Nrf2 and Nrf-Dependent Gene Expression in Human Skin

12 Mar 2009

Abstract excerpt

Human skin is constantly exposed to UV light, the most ubiquitous environmental stressor. Here, we investigated the expression and regulation of Nrf1-3, transcription factors crucially involved in protection against oxidative stress in human skin cells in vitro, ex vivo, and in situ. In particular, we examined whether alpha-MSH, a UV-induced peptide, is capable of modulating Nrf2 and Nrf-dependent gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circadian rhythm and melatonin
Share to Genomics, phytochemicals, and oxidative stress
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19282378
DOI: 10.1210/en.2008-1315

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

α-Melanocyte-Stimulating Hormone Counteracts the Suppressive Effect of UVB on Nrf2 and Nrf-Dependent Gene Expression in Human SkinPMID 19282378Read ↗

Effect of ultraviolet radiation on the Nrf2 signaling pathway in skin cellsSemantic proximity Read ↗

The activation of PPARγ by 2,4,6-Octatrienoic acid protects human keratinocytes from UVR-induced damagesSemantic proximity Read ↗

Protein Kinases and Transcription Factors Activation in Response to UV-Radiation of Skin: Implications for CarcinogenesisSemantic proximity Read ↗

The Antiaging Activity of Ergothioneine in UVA-Irradiated Human Dermal Fibroblasts via the Inhibition of the AP-1 Pathway and the Activation of Nrf2-Mediated Antioxidant GenesSemantic proximity Read ↗

Natural protection against oxidative stress in human skin melanocytesSemantic proximity Read ↗

Regulatory Mechanisms of Natural Active Ingredients and Compounds on Keratinocytes and Fibroblasts in Mitigating Skin PhotoagingSemantic proximity Read ↗

MC1R: Front and Center in the Bright Side of Dark Eumelanin and DNA RepairSemantic proximity Read ↗

Effects and Mechanism of Nicotinamide Against UVA ‐ and/or UVB ‐mediated DNA Damages in Normal MelanocytesSemantic proximity Read ↗

RNA-Seq analysis revealed genes associated with UV-induced cell necrosis through MAPK/TNF-α pathways in human dermal fibroblast cells as an inducer of premature photoagingSemantic proximity Read ↗

Distinctive molecular responses to ultraviolet radiation between keratinocytes and melanocytesSemantic proximity Read ↗

MC1R and NR4A receptors in cellular stress and DNA repair: implications for UVR protection.Semantic proximity Read ↗

5,7‐Dimethoxyflavone, an activator of PPARα/γ, inhibits UVB‐induced MMP expression in human skin fibroblast cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.